GSK: Laurent Bessemans & Pascal Silversmet

A certain approach of the automation for laboratory : EasyLab, the GSK Vaccines R&D Lab Automation team

EasyLab is responsible for the implementation of automation within the GSK R&D Laboratories worldwide. Based on a conceptual approach of the automation for laboratories, project management capabilities, partnerships and tools, this talk covers how EasyLab implements fit for purpose automated solutions and supports scientists on a daily basis.


Janssen Pharmaceutica: Hugo Bohets, PDMS _ pre-formulatie 

Using automation as a versatile adaptive platform for formulation development

In order to make poorly soluble drugs bio available different enabling strategies are possible such as Solid dispersions, precipitation inhibition and nano milling. All these approaches are linked to a wide range of excipients. To screen the effect of most common excipients on the drug ability one obtains easily hundreds of ratios and/or combinations. This especially when investigating the effects of combination of multiple excipients.

It is clear that automation is a good tool to master this wide range of experiments by executing the tests in simultaneous or semi simultaneous way.

Examples will be shown on how we apply such strategies for enabling formulations. It will be shown how we use a single robot to run a variety of protocols without losing robustness and maintainability. We also will discuss the interaction between multiple platforms and their strong and weak points.


UCB BioPharma: Eric De Maesschalk, Head Global e-Analytics, Corporate Analytical Sciences 

Business case : Paperless journey @ UCB : wonders and dark side of progressive e-Transformation of laboratory processes.

UCB has been working for years to evolve from hybrid (paper + electronic systems to store the information) to paperless / e-laboratory processes.  The computerized systems landscape developed progressively to become a complex entanglement of applications, tools and processes.  Looking at it we can say “wow”  look at all these nice things we’ve put in place (THE WONDERS).

However, when launching a large Knowledge Management program aiming at extracting analytical data from the landscape, and trying to mix them in order to build knowledge, then your reaction becomes “OOOOPS”… How will we be able to combine and correlate data which are not necessarily structured and aligned (coding, naming convention) for that purpose? (THE DARK SIDE)



Eric graduated in Clinical Chemistry and Medical Biology. He has spent 31 years in highly regulated pharmaceutical companies: GSK, Pfizer, Phibro Animal Health and UCB BioPharma.

Eric has 29 years of experience in computerized systems qualification and validation including IT infrastructure (GMP, GCP, GLP, GPvP).  His current position at UCB Pharma is Head of Global e-Analytics, Corporate Analytical Sciences, where he has to define, with his business partners, the long term strategy for, and ensure the integration and control of, the computerized systems landscape supporting commercial and development analytical laboratories implemented across UCB sites (e.g. GLIMS, ELNs, statistical application, central chromatography, scientific data management system, etc.).


Thermo Fisher Scientific: Maartens Van As

LIMS Solutions from R&D through to QA/QC 

Our LIMS and laboratory software solutions enable customers to increase efficiencies in their laboratories by eliminating manual steps.  Our Laboratory Information Management Systems (LIMS) fit to your workflows to automate processes, giving analysts’ more time to work in the lab.  We supply LIMS, LES and SDMS in one complete solution – connecting valuable data and making it easily sharable across your organization to deliver knowledge to those who need it.


RICBart Tienpont, Gas Phase Specialist

Taking pyrolysis a step further

While analytical pyrolysis was already introduced in the early 60’s as a convenient tool for the thermal breakdown and subsequent analysis of polymers the technique has not reached its final state. So far gas chromatography has been considered as the principle technique allowing hyphenation to pyrolysis. However, as pyrolysis is in most cases very complex the scope of reaction products lays far beyond the analytical range of gas chromatography.

During the last decade some timid steps have been taken to couple pyrolysis to HPLC or related techniques. In most cases a commercially available pyrolysis unit was modified to allow connection to an injection valve. Alternatives were found in collecting the pyrolysate in a cryo-cooled loop or vial.

This group has introduced an in-vial pyrolysis (PyroVial). Pyrolysis is carried out in a 2 mL autosampler vial placed in a XYZ robot for automated pyrolysis. Analysis of the volatiles is performed by headspace analysis while the semi- and non-volatiles are extracted from the pyrolysate with an organic solvent. The features of the PyroVial are such that all chromatographic techniques can be applied. Moreover, pre- and post-pyrolysis treatment of the sample is possible.

This presentation discusses current state-of-the-art of the Pyrovial and it will be positioned towards ‘classical’ Pyr-GC(MS). Practical aspects will be discussed and illustrated with applications in which the interfaces are applied for pyrolysis but also as an micro-scale reactor for high temperature reactions in the field of petrochemical and biological conversions.


Beckman Coulter: Stefan Overkamp

Augmented automation software for confidence in error-free system operation and data quality

Well engineered hardware in laboratory automation is standard since many years across most suppliers and the differences become more and more insignificant.

The trick for successful automation implementation in real research lab environments becomes one of the interface between the scientist and the hardware – the automation control software.

In this presentation you will learn new tools implemented by Beckman Coulter to ensure a high level of confidence in operating an automated system error-free even by unexperienced users. 

Using icon driven simple execution modules, cameras and self-learning algorithms the new Biomek Method Launcher takes the simplicity of interaction with an automated liquid handling system to a new level.

At the same time a powerful database driven data-handling tool guarantees your data are taken care of just as seriously as your samples. Because in the end it is the data that make up good science, and data handling – from acquisition through tracking and interpretation to report and using it to drive the operation – must be an integral part of a powerful automation system. For automation tools that allows science to determine your experiments, and not the lab equipment’s capabilities your science. 


Agilent Technologies: Michel Elshof

OpenLAB : `Overcome the limitations of paper-based storage `

Whether you’re a contract lab whose business depends on your reputation, or a production facility striving for the best product quality, your scientific data is your most important asset. Enjoy peace of mind knowing that your information is protected from unauthorized modifications and loss, and is easily accessible to facilitate inspections or investigations. 

Ensure all important data is securely stored 

Regulations often require you to store data files for a prescribed number of years. Content import tools make certain that all important instrument data is automatically secured at the appropriate time. 

Prevent fraud and identify unauthorized changes or deletions 

With OpenLab ECM XT, you can store data and files in a secure location with password-protected access. The software also tracks and saves every version of e-record and data from selected data systems. So you can recover previous versions and review the changes. 

Reduce the time—and cost—of managing paper reports and records 

Storing years of paper reports and records take up a lot of storage space (on-site or off-site) and is costly. OpenLab ECM XT simplifies filing, and organizing, with automated content import.


Synchron: Niels Kruizen

Serial processing in laboratory automation: the path to industry 4.0 ?  

In this presentation we will give some examples of developments in lab automaton which we have approached with serial processing like used in production processes . One of these examples is the development of a ultra high throughput DNA extraction system in a small factory like set-up that fits a lab environment. 


Instrument Solutions: Jan Volkers

English title and abstract coming soon.

Volledige monstervoorbereidingsproces van Glyfosaat/AMPA met on-line µSPE

Automatisering van de monstervoorbereiding is voor veel laboratoria steeds meer een belangrijk speerpunt.

Het spreekt voor zich dat met het elimineren van arbeidsintensieve monstervoorbereidingsstappen zoals bijvoorbeeld voor de (off-line) µSPE analyse van Glyfosaat/AMPA veel tijd wordt bespaard.

Glyfosaat is een chemische verbinding uit de groep Fosfaten en 's werelds meest gebruikte herbicide/bestrijdingsmiddel. Het werd voor het eerst in 1950 gemaakt en gebruikt. Vanaf die tijd is het dus in ons milieu geïntroduceerd.

Glyfosaat wordt voornamelijk omgezet door micro-organismen. De afbraak verloopt via de verbinding Aminomethylfosfonzuur (AMPA), dat daarom ook een analytische relevantie krijgt.

Beiden worden gecontroleerd in het milieu en inmiddels ook in voedingsmiddelen.

Voor deze analyse is LC-MS/MS in combinatie met derivatisering van de analyten de meest gebruikte techniek. De toevoeging van online µSPE biedt twee belangrijke voordelen:

  • Met één verrijkingsstap worden de haalbare detectie- en bepalingslimieten verbeterd
  • Methode matrixcomponenten worden verwijderd en neveneffecten zoals iononderdrukking worden verminderd. Dit is vooral voor de LC-MS koppeling een serieus voordeel.


Het volledige monstervoorbereidingsproces is met de on-line µSPE oplossing van Instrument Solutions geautomatiseerd. De derivatisering wordt uitgevoerd op de Chronect modules van Axel Semrau, zodat detectiegrenzen, reproduceerbaarheid en ook de factor tijd tot een maximum geoptimaliseerd zijn.


MicroTechniX: Jean-Paul Sanders

Digitizing the interpretation process in environmental monitoring

This article is all about a reality case at a pharmaceutical company. It describes the way it takes to make decisions in pharmaceutical companies to come to an automated system which digitizes the interpretation process in environmental monitoring. I also answers questions frequently asked by people involved in EM.


Exposants Lab Automation Day